The global prevalence of infertility has been steadily rising. The number of cases of men in the UK is increasing rapidly, reaching a peak in 2013. The increase is attributed to the aging of the population and the rising prevalence of male factor infertility [
]. The increase in infertility is driven by the growing prevalence of male factor infertility, and the increasing global prevalence of male factor infertility [
To the best of our knowledge, the treatment of male factor infertility has received limited research. The first-line treatment was a combination of Clomiphene Citrate and Femara (Femara) [
Clomiphene is a selective estrogen receptor modulator that stimulates the growth of follicles in the ovaries. Femara is also approved for use in the management of infertility caused by other conditions, including polycystic ovary syndrome (PCOS), and for treatment of ovulatory dysfunction. However, its use in male factor infertility has not been established. The use of Femara has been associated with an increase in the risk of ovarian hyperstimulation syndrome, a potentially life-threatening complication of Femara use [
The development of a new agent, clomiphene citrate, and its subsequent approval in the USA in 2010 for male factor infertility was announced in March 2011 [
,
The approval of clomiphene citrate for male factor infertility was announced in February 2012, following the publication of data on the impact of clomiphene citrate use on fertility in a cohort of men with anovulatory cycles and a review of the literature [
In addition, the approval of clomiphene citrate in the UK for male factor infertility in 2012 [
] is pending and may have implications for the future treatment of this condition. The use of clomiphene citrate has not been directly evaluated in patients with male factor infertility and may be an alternative to Femara in the management of the condition. However, the effects of clomiphene citrate on fertility in males with male factor infertility are not well established and should be considered [
The aim of this study was to evaluate the effect of clomiphene citrate and its new agent, clomiphene, on fertility in patients with male factor infertility.
The study was performed in accordance with the Declaration of Helsinki. A detailed description of the protocol and patients are provided in a previous publication [
The Ethics Committee of the Department of Obstetrics and Gynaecology, The University of Manchester, UK (Ref: B611-0307, B611-0307/1, UK) approved this study, and all participants gave their informed consent. A written informed consent was obtained from each participant.
The Ethics Committee of the Department of Obstetrics and Gynaecology, The University of Manchester, UK (Ref: B611-0307, B611-0307/1, UK) approved this study.
This was a phase III, randomized, double-blind, parallel-group trial of clomiphene citrate in men with male factor infertility. The trial was performed at The University of Manchester. The trial was conducted in accordance with the protocol and the Declaration of Helsinki and the study protocol was approved by the ethics committee. The participants were randomized to clomiphene citrate or placebo, and they were advised to take one 50 mg tablet of clomiphene citrate daily for a minimum of 7 days, at the end of the treatment period. The study was conducted in compliance with the recommendations for the use of clomiphene citrate in clinical practice [
During the study period, a total of 488 participants (mean age, 35.9 ± 4.9 years) completed the clinical interview for the diagnosis of male factor infertility. The participants were informed about the study and provided written informed consent to participate. Participants were informed about the purpose of the study and their right to withdraw from the trial if they failed to attend the meeting. Participants gave their informed consent for the study after completing a detailed questionnaire. The study was conducted in accordance with the Declaration of Helsinki. The protocol was approved by the Ethics Committee of The University of Manchester, UK.
The study protocol was registered in the Dutch clinical trials registry (NCT01342520). The protocol has been developed to facilitate the clinical management of male factor infertility.
Clomid tablets are primarily used to treat infertility in women.
Clomid is classified as Hormonal Therapy. It is composed of Clomiphene Citrate. There are certain hormones that support the growth and release of a mature egg in women. This process is called Ovulation. Clomid stimulates the growth of said hormones and assists in ovulation by blocking estrogen receptors at the hypothalamus. It is not recommended to women whose ovaries are incapable of making eggs properly.
You can now buy Clomid online from emeds Pharmacy by simply completing the online ordering process. There is no need for you to physically visit a pharmacy or book an appointment with a doctor as you can safely and securely have medicines delivered to your home or other choice of location. If you have any queries relating to ordering Clomid online via our website, feel free to contact us on 0311 113 6337 where a qualified member of the team will be available to assist you.
Generally, Clomid is taken for 5 days, starting on the 5th day of your menstrual cycle. The specific dosage is determined by the doctor based on your specific medical condition and response to therapy. A pelvic examination is required before each treatment cycle. Do not take it longer than prescribed by your doctor. Long-term treatment with Clomid is not recommended. It should not be taken for more than 6 cycles. Ideally, it is administered orally one tablet a day, as prescribed. Please consult your doctor, or contact our dedicated pharmacist at emeds Pharmacy for additional guidance.
Every medicine can cause side effects, even if they are rare. Common side-effects of Clomid include;
Contact your doctor immediately if these or other side-effects appear. Its warnings include;
Generally, emeds Pharmacy is taken for 5 days, starting on the 5th day of your bleeding cycle. The specific dosage is determined by your doctor based on your specific medical condition based on your ovaries (pelvic/baldness/testicular pain). Your doctor will assess your menstrual cycle response to treatment and may increase the dosage based on your doctor’s clinical need. Most women will respond to Clomid from the 5-day mark. ItsCommon side-effects are;
As the brand Emeds Pharmacy uses the generic medication, it is not prescribed to women. Its specific aim is to provide safe and effective treatment for women “ “ with a specific medical condition. However, it is always recommended to consult your doctor before starting any medication “ “ for sexual health assessment.
Clomid is available in various strengths, including 25mg and 50mg. However, its specific strength is not fully understood, so any guarantee regarding its safety is important.
It is not recommended to drink alcohol while taking Clomid as it can increase the risk of side effects.
It takes 30 to 60 minutes for Clomid to startlide.
We have with us superior quality CLOMIFENE CITRATE (CLOMID) which are well known among our customers for their high efficiency. Our offered medicines are primarily used for under doctors guidance in various hospitals and clinics.
Mehadia Tradelinks is the leading exporter of pharmaceutical products high quality Anti-Cancer Drugs, Anti-Cancer Medicines, Hepcinat, Hepcinat LP, Ledifos, Sofosbuvir, Trastuzumab, Lenvatinib, Sofovir, Finpecia, Dutas, Sofosbuvir & Ledipasvir, Hepatitis Medicines, HIV Products, Generic Medicines, Tenofovir, Anti-Rabies Vaccine, Hepatitis Vaccine to name a few.
We have strong global networks in United States, Canada, Italy, France, Germany, Brazil, United Kingdom, China, Japan, Philippines, South Korea, Russia, Ukraine, Dubai, United Arab Emirates, Malaysia, Saudi Arabia, Thailand, Vietnam, South Africa, Nigeria, Singapore, Zimbabwe, Sudan, South Sudan, Uganda, Congo, Chad, Cameroon, Mali, Morocco, Somalia, Bangladesh, Sri Lanka, Maldives, Nepal, Middle East and South East Countries.
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It can be used alone or with other medications to treat the following conditions:
It is advised to take Furosemide with food or milk to reduce the chance of getting the infection. Take this tablet with a glass of water 30 minutes before or 2 hours after taking the course. Avoid breaking or crushing the tablets. Take Furosemide with or without food to get the full benefits. It is generally recommended to take Furosemide with a meal or snack to reduce the chance of getting the infection.
The tablet can be taken with or without food to reduce the chance of getting the infection.The tablet is not indicated for the treatment of genital herpes and is not recommended for the treatment of HIV infection. Furosemide can be used to treat the following conditions in women:Women of childbearing potential: This tablet is used to treat this condition and helps to control the infection by decreasing the growth of the infected baby.It is advised to take Furosemide with or without food to reduce the chance of getting the infection.Salt Composition in both
Salt Composition
Clomiphene 50mg(same for both)
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